Macrophage Responses to Silica Nanoparticles are Highly Conserved Across Particle Sizes
نویسندگان
چکیده
منابع مشابه
Differential proteomics highlights macrophage-specific responses to amorphous silica nanoparticles.
The technological and economic benefits of engineered nanomaterials may be offset by their adverse effects on living organisms. One of the highly produced nanomaterials under such scrutiny is amorphous silica nanoparticles, which are known to have an appreciable, although reversible, inflammatory potential. This is due to their selective toxicity toward macrophages, and it is thus important to ...
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Amorphous silica particles, such as nanoparticles (<100 nm diameter particles), are used in a wide variety of products, including pharmaceuticals, paints, cosmetics, and food. Nevertheless, the immunotoxicity of these particles and the relationship between silica particle size and pro-inflammatory activity are not fully understood. In this study, we addressed the relationship between the size o...
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We have investigated emulsions stabilised solely by partially-hydrophobised fumed silica particles which consist of a mixture of primary particles and irregularly-shaped fused aggregates and larger agglomerates. The particle wettability is controlled by varying the extent of hydrophobisation of their surfaces. This, in turn, controls the contact angle between the oil-water interface and the par...
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1Howard Hughes Medical Institute, the Salk Institute for Biological Studies, La Jolla, CA 92037 2McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, 02139 3Center for Learning and Memory, Department of Neuroscience, University of Texas, Austin, TX 78712-0805, USA 4Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093 ...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2008
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kfn250